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21 Jun Follicular dendritic cells (FDCs) are stromal cells residing in primary There, they play a crucial role in B-cell activation and affinity maturation of antibodies. Their main function being the presentation of native antigen, in the. 21 Jun Their main function being the presentation of native antigen, in the form of immune . Follicular dendritic cells are not the sole stromal cell of SLOs. .. Early studies assessing the influence of FDCs on B-cell activation were. A need for antigen-processing and presentation to B cells is not widely appreciated. However, cross-linking of multiple B cell receptors (BCRs) by T- independent.
17 Jan Follicular Dendritic Cell Activation by TLR Ligands Promotes .. (GCs) in lymphoid tissues where self-reactive B cells expand and differentiate. The tumor cells in follicular dendritic cell sarcoma show cytologic features reminiscent of . including activation of B cells and maintenance of immunologic memory. Unlike other DCs, FDCs do not process antigen for presentation to T cells. Follicular dendritic cells (FDCs) are found in all secondary lymphoid tissues, where presentation to B‐lymphocytes; HIV reservoir; prions; follicular lymphoma.
1 Dec The follicular dendritic cell (FDC) is known as a key cellular in which Ag- activated B cells are able to proliferate and differentiate and to provide as treatment of B cell lymphoma because IL presentation by FDC may. 8 Jun Follicular stromal cells, including FDCs, are a source of the chemokine CXCL13 In vitro studies demonstrated that B cell activation by immune . that antigen encounter at this time point required presentation by FDCs, when. Follicular dendritic cells (FDCs) are cells of the immune system found in primary and secondary lymph follicles of the B cell areas of the lymphoid tissue. . Activated B-cells with low affinity to antigen captured on FDCs surface as well as .